Study on Biological Function of NMN and Various Ways of Ingestion

β-Nicotinamide Mononucleotide (NMN) is a nucleotide derived from ribose and nicotinamide. NMN is a precursor of nicotinamide adenine dinucleotide (NAD+). Studies have shown that mammals cannot directly ingest NAD+. In order to maintain the balance of NAD+ in the body, the biosynthesis of NAD+ in mammals mainly depends on the nicotinamide salvage pathway involving precursors such as NAM and nicotinamide ribonucleic acid. At present, the precursors of nicotinamide ribonucleic acid mainly include the following two compounds: β-nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR). After NR enters the cell, it will be converted into NMN under the catalysis of "nicotinamide riboside kinases (NRKs)".

NMN is transformed into NAD+ in the human body to exert its physiological functions, such as activating NAD+ substrate-dependent enzyme Sirt1 (histone deacetylase, also known as sirtuin), regulating cell survival and death, maintaining redox state, etc.

In recent years, research on the biological functions of NMN has been increasing, such as:

1. Anti-aging and age-related physiological decline related diseases

2. Repair DNA damage

3. Neurovascular regeneration, mitochondrial protection, anti-inflammation, anti-apoptosis

4. Improve the energy state of mitochondria and promote capacity generation

5. Brain health-related: ischemic injury, Alzheimer's disease-related, improving brain microvascular endothelial function, improving cognitive impairment

6. Heart health related

7. Diabetes related: regulate insulin secretion, protect islet function

8. Weight control

9. Promote the expansion of mesenchymal stem cells, promote osteogenesis and reduce fat synthesis

10. Improve dark vision and retinal function

11. Acute kidney injury

At present, more than 30 countries around the world have added NMN-related clinical trials. In Japan, NMN can be used as a common food raw material, combined with other functional ingredients (such as beauty, sleep aid), and the form also covers from tablets, A range of applications from powders to beverages and snacks.

The anti-aging and anti-aging functions of NMN have rapidly increased consumers' attention. With the continuous popularization and deepening of consumption upgrades and healthy consumption awareness, more and more consumer groups of different ages have begun to pay attention to how to delay aging with the help of technological innovation, so as to maintain their own health and enhance vitality.

We provide high-quality and high-purity β-nicotinamide mononucleotide (NMN) raw materials, and the products are exported to Europe, America, South Korea, India and other parts of the world. If you are interested in our products, please feel free to contact us, we will be very happy Happy to provide any information you need.

Tag: NMN , Anti-aging, food raw material

Supplier Introduction: China glutathione supplier and NMN manufacturer GSHworld, the company mainly develops biotechnology and industrialization. As a global pioneer in enzymatic catalytic ATP regeneration technology, our company advocates green production and is committed to providing customers with better and more environmentally friendly products and services. Glutathione Manufacturer,NMN Factory,Citicoline Sodium supplier,China NMN manufacturers