Acetyl glutathione increases absorption and availability

Alcohol-related cancers are concentrated in oral cancer, larynx cancer, esophageal cancer, stomach cancer, liver cancer, colorectal cancer, breast cancer (female), etc. This may be related to the absorption of alcohol by our entire digestive tract, which enters the blood circulation and is transported throughout the body .

Ethanol is oxidized to acetaldehyde. Relying on the ADH system, ethanol is oxidized into toxic acetaldehyde.

Acetaldehyde is oxidized to acetic acid. Relying on the ALDH system, toxic acetaldehyde is oxidized into non-toxic acetic acid. Acetaldehyde concentration in the blood is mainly determined by ALDH.

Acetic acid participates in the citric acid cycle to generate energy, water, carbon dioxide, etc., and a small part of it generates protein and fat for use by the human body.

Alcohol dehydrogenase (ADH), microsomal cytochrome P450 2El (CYP2E1) and aldehyde dehydrogenase (ALDH) are the absolute factors that determine the differences between each individual. The heritability of alcohol consumption is related to the heredity of these three enzymes. Moreover, these three enzymes are highly genetically polymorphic, and this polymorphism determines drinking behavior.

The enzymes that detoxify alcohol are limited in the body. Excessive drinking and excessive consumption of detoxification enzymes will cause alcohol and acetaldehyde to accumulate due to insufficient detoxification, resulting in widespread oxidative stress toxicity in the body.

Reduced glutathione infusion has always been a commonly used clinical drug for the treatment of alcoholic hepatitis. It can effectively scavenge free radicals, stabilize and protect liver cell membranes, and is often used in the rescue of acute liver injury and alcoholism. 

Acetyl glutathione can be taken as an oral dosage form, which can increase absorption and utilization, protect the antioxidant properties of glutathione, and provide stable release. In practice, it has obvious effects in assisting alcohol metabolism, relieving hangovers, and relieving hangovers and headaches.

Tag: Glutathione GSH

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