Six Questions About NMN - Knowledge

Six Questions About NMN

Jun 26, 2023 / Author: China Glutathione suppliers & NMN manufacturers

1. What is NAD+?

NAD+: Nicotinamide adenine dinucleotide, referred to as coenzyme Ⅰ, as an essential coenzyme in redox process and NAD+-dependent adenosine diphosphate ribosyltransferase, ring-sourced ADP ribose polymerase, type Ⅲ histone deacetylation Catalase, the only substance that can be used, participates in various physiological activities such as cellular material metabolism, energy synthesis, and cellular DNA repair.

2. What is NMN?

NMN is the abbreviation of β-Nicotinamide Mononucleotide, which naturally exists in living cells and is the precursor of coenzyme 1 NAD+ (nicotinamide adenine dinucleotide). Properly prolong life. It is an important energy metabolite called nicotinamide adenine dinucleotide (NAD+) that really does the antiaging work.

3. Can NMN really anti-aging?

"Nature" included it in the first echelon when it selected the most potential anti-aging substances in 2020. The anti-aging function of NMN has been generally recognized by the scientific community today. Since 2013, hundreds of experimental papers related to NMN have been published in well-known scientific journals such as "Cell", "Nature" and "Science".

4. What is the difference between β-NMN and α-NMN?

NMN is divided into β-NMN and α-NMN. The two look very similar. The only difference is that the position of a chemical bond is different, resulting in a different spatial structure between the two, which ultimately leads to different biological activities: β-NMN has biological activity, and α-NMN has biological activity. NMN has no biological activity, which means that what really works is β-NMN. No matter which production process is used, both β-NMN and α-NMN will be produced in each batch of NMN raw materials. Therefore, the high purity of pure NMN does not mean that it is more effective, and it must be proved that the high content of β-NMN is really good.

5. Is it safe to take NMN?

In a large number of experiments with NMN, no obvious drug-induced side effects occurred. Relevant studies at home and abroad have shown that no side effects have been found when the dosage is many times higher than the normal dosage. The first-phase clinical trials of the drug by three foreign research institutions including Harvard Medical School have proved that taking NMN is safe for the human body.

6. What is the safe dosage of NMN?

In 2016, a research team led by Professor Shinichiro Imai of the University of Washington School of Medicine conducted a long-term experiment with oral administration of NMN to mice. Experiments have found that long-term oral administration of NMN to mice at a dose of 100mg/kg/d can slow down most of the physiological decline associated with aging. The equivalent dose converted into humans is 8mg/kg/d, which is equivalent to about 520mg per day for an adult weighing 65kg.

Combined with the conclusion that "a single oral administration of 500 mg of NMN is safe" from the NMN clinical research published in 2020, it is recommended that the safe dosage of NMN be about 500 mg per day.

Of course, we recommend that you always consult your healthcare provider for a diagnosis, accurate medical information, and approval before taking any supplements.

Tag: NMN

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