Mar 16, 2021 / Author: China Glutathione suppliers & NMN manufacturers
Nicotinamide Mononucleotide plays an important role in the energy production of human cells. It is involved in the synthesis of intracellular NAD (nicotinamide adenine dinucleotide,β-Nicotinamide Mononucleotide an important coenzyme for cell energy conversion). Nicotinamide mononucleotide, the substance originally exists in the human body,β-Nicotinamide Mononucleotide but decreases with age. Earlier experiments confirmed that nicotinamide mononucleotide W+NMN can increase NAD in various organs in experimental mice,β-Nicotinamide Mononucleotide thereby inhibiting the aging of nerves and blood vessels,β-Nicotinamide Mononucleotide and improving the symptoms of diabetes.
Nicotinamide mononucleotide is a naturally occurring biologically active nucleotide. NMN has two irregular forms,β-Nicotinamide Mononucleotide α and β;β-Nicotinamide Mononucleotide β isomer is the active form of NMN with a molecular weight of 334.221. Because nicotinamide belongs to vitamin B3,β-Nicotinamide Mononucleotide NMN belongs to the category of vitamin B derivatives. It is widely involved in many biochemical reactions of the human body and is closely related to immunity and metabolism. NMN can also be synthesized by endogenous substances: 1 molecule of nicotinamide and 1 molecule of 5-phosphoribosyl-1-pyrophosphate (PRPP) are catalyzed by nicotinamide phosphoribosyl transferase (NAMPT or NAMPRT) to generate 1 molecule of NMN and 1 molecule of pyrophosphate (PPi). In addition to nicotinamide,β-Nicotinamide Mononucleotide NMN can be generated. One molecule of nicotinamide riboside (NR) is phosphorylated under the catalysis of nicotinamide riboside kinase (NRK) to generate one molecule of NMN.
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