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Citicoline is a mononucleotide composed of ribose, cytosine, pyrophosphate and choline. As a component of cell membrane structure, citicoline is essential in maintaining homeostasis, maintaining membrane-associated enzyme activity, coupling receptors and intracellular signals, and nerve impulse conduction.
Product description of Citicoline Powder:
Loss on drying
Not more than 6%
Not more than 5ppm
24 months when properly stored.
In the central nervous system, 80% of phospholipid synthesis is regulated by changes in citicoline concentration, and citicoline formation is the rate-limiting step in the synthesis of phosphatidylcholine through the Kennedy cycle. Exogenous administration of citicoline can accelerate phospholipid synthesis, promote the rapid repair of damaged cell surface and mitochondrial membrane, maintain the integrity of cell membrane and cell energy metabolism.
Citicoline's mechanism of action:
Citicoline has neuroprotective effects in the first few hours of cerebral ischemic onset, and enhances neuroplasticity and neurorestoration in the subacute phase (days to weeks). These effects are mainly achieved through the following mechanisms: repairing neuronal cell membranes by increasing phosphatidylcholine; stabilizing the neurotransmitter system by increasing the synthesis of acetylcholine and catecholamines; reducing the accumulation of free fatty acid (FFA) in ischemic brain tissue ; Promote energy metabolism in brain tissue.
Radiotracer studies have shown that oral citicoline can be rapidly and completely absorbed and hydrolyzed in the intestinal wall to choline and cytidine, which enter various biosynthetic pathways that use citicoline as a mediator, It has the same bioavailability and similar pharmacokinetic characteristics as intravenous citicoline. Exogenous citicoline is widely distributed in the cortex, white matter and central gray matter nuclei, and its elimination is extremely slow, with a small amount excreted daily through urine, feces and respiratory routes.
GSH BIO-TECH is an innovative high-tech enterprise with enzyme catalysis technology in the field of synthetic biology as the core and cross-application of multidisciplinary technologies.We provide high quality Citicoline Sodium and Citicoline, both of which are produced in GMP certified workshops, with a purity of more than 99%, and the density can be customized, Should you have interests in us, please don't hesitate to get in touch with us，we will be pleased to supply any further information you require.
1.More Professional service in active pharmaceutical ingredients exporting field
2.Better manufacture ability
3.Various payment term to choose:T/T,Western Union,L/C,Paypal
4.High quality/Safe material/Competitive price
5.Small order available
7.More safe and fast transport
8.OEM design for all customers
Q: What’s is your shipping service?
A: We can provide services for vessel booking, goods consolidation, customs declaration, shipping documents preparation and delivery bulk at the shipping port.
Q: Can you do our own packaging?
A: Yes, you just provide the package design and we will produce what you want. We also have the professional designer can help you do the packaging design.
Q: How long is your delivery time?
A: The general delivery time is 7 days after receiving your order confirmation. If we have the goods in stock, it will only take 1-2 days.
Oct 20, 2023