Jul 25, 2022 / Author: China Glutathione suppliers & NMN manufacturers
Glutathione (GSH) is the most abundant low-molecular-weight thiol compound in cells. It exists mainly in the reduced form in eukaryotic cells, but it can also be oxidized to glutathione disulfide. (GSSG) or in combination with other molecules such as GSSG-CoA and GSSG-Cysteine. In the cell, about 90% of GSH is distributed in the cytoplasm, and a small amount is distributed in subcellular organelles, such as mitochondria, nucleus and endoplasmic reticulum. Relatively low levels of GSH can also be found in the extracellular space. The steady-state level of intracellular GSH depends on the synthesis, hydrolysis, and recycling of GSSG and the balance between the intracellular reduction and oxidation states.
GSH imbalance is observed in a variety of pathological conditions, including cardiometabolic and cardiovascular disease, tuberculosis, AIDS, diabetes, neurodegenerative diseases, Alzheimer's disease, infertility, and cancer. In some animal experiments, it was found that GSH has the functions of resisting oxidative stress, detoxification, improving immunity, and promoting growth and development. Adding it to the feed will be beneficial to the healthy breeding of animals.
Glutathione is the most abundant non-protein thiol peptide in cells. In cells, glutathione is capable of scavenging free radicals, transducing signals, maintaining membrane integrity, and serving as a source of nitrogen and sulfur during nutrient limitation.
GSH is an abundant non-enzymatic antioxidant in mammalian cells, an important mechanism of intracellular defense against oxidative stress, and an important antioxidant system defense line against ROS.
When immune cells attack pathogens, they release some strong oxidative chemicals that are harmful to body cells, and GSH can neutralize these strong oxidative chemicals to protect immune cells.
Combining with GSH is a very important means of detoxification in the enzymatic or non-enzymatic reactions that take place in cells. Clinically, GSH can also be used as an antidote for the detoxification of acrylonitrile, fluoride, carbon monoxide, heavy metals, aflatoxins and organic solvents.
GSH is a new type of feed additive that can improve the immune function of animals, save feed, promote animal growth and improve meat quality. Adding GSH to the diet can promote the healthy breeding of livestock and poultry, reduce the dosage of antibiotics, improve the quality and safety of meat products, and has a good application prospect.
It is believed that glutathione will have broader development prospects in animal production in the future, and will also have a positive impact on the development of livestock and poultry industry.
Supplier Introduction: China glutathione supplier and NMN manufacturer GSHworld, the company mainly develops biotechnology and industrialization. As a global pioneer in enzymatic catalytic ATP regeneration technology, our company advocates green production and is committed to providing customers with better and more environmentally friendly products and services. Glutathione Manufacturer,NMN Factory,Citicoline Sodium supplier,China NMN manufacturers
Oct 20, 2023