Dec 03, 2021 / Author: China Glutathione suppliers & NMN manufacturers
Carnosine (English: L-Carnosine), the scientific name β-alanyl-L-histidine, is a dipeptide molecule composed of two amino acids β-alanine and L-histidine. It is found in vertebrate brains. And skeletal muscle tissues in high concentrations. Studies in the United Kingdom, South Korea, Russia and other countries have shown that carnosine can scavenge reactive oxygen free radicals (ROS) and α-β unsaturated fatty aldehydes that are formed by the over-acidification of fatty acids in cell membranes during oxidative stress. It has antioxidant properties Efficacy and so on. At the same time, carnosine also has high medicinal value. Supplementing carnosine can alleviate some neurological diseases, including Alzheimer's disease, Parkinson's disease, cancer and so on.
Carnosine is mainly found in metabolically active organs, such as skeletal muscle (content is 1-20 mmol/Kg) and the brain. The carnosine in muscle has physiological functions such as physiological pH buffering, scavenging free radicals, enhancing antioxidant capacity, and affecting calcium ion regulation. In 1900, Russian scholar Gulewitsch isolated carnosine for the first time from beef extract, which was the first representative bioactive peptide isolated from natural raw materials.
Since Gulewitsch first isolated carnosine, for more than 100 years, scholars from various countries have extracted and isolated different types of carnosine from different muscle tissues, such as anserine (β-alanyl-1-methyl-L-histidine, Anserine) , Cetyl carnosine (β-alanyl-3-methyl-L-histidine, Balenine, also known as snake carnosine, Ophidine,), decarboxyl carnosine and other dipeptides, have their own advantages.
A large number of studies have shown that carnosine has anti-aging, anti-glycation, anti-oxidation and chelation effects, and is widely used by many cosmetics manufacturers due to its high activity, strong anti-oxidation, small molecule, and high safety. As a bigwig in the antioxidant world, carnosine has its own unique mechanism of action!
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