Popular Science of Glutathione Raw Materials

Glutathione is a tripeptide that exists widely in nature; it mainly exists in the cytoplasm and plays a role in various cellular biochemical functions. The sulfhydryl group of cysteine in reduced glutathione is highly nucleophilic, so it is the main target structure for electrophiles stimulated by xenobiotics or their metabolites, thereby protecting the main nucleophilic site, The latter, if affected, can lead to cellular damage. Once it reacts with organic oxidative metabolites, it can form easily metabolized and low-toxic compounds.

The level of intracellular glutathione is altered and decreased in many conditions such as malnutrition, various diseases, chemical poisoning and taking drugs. In animals and humans, reduced glutathione has a protective effect on cytotoxicity induced by many substances such as salicylic acid, organophosphate pesticides and alcohol. In vivo animal studies have shown that reduced glutathione does not affect intestinal motility, blood pressure and respiration, and does not cause ECG changes.

The physiological functions of glutathione mainly include the following aspects.

(1) It can effectively eliminate free radicals and prevent free radicals from harming the body. As a free radical scavenger, it can have a strong inhibitory effect on excessive free radicals produced by the body's metabolism to damage biofilms, invade life macromolecules, promote body aging, induce tumors or arteriosclerosis; it can remove lipids Peroxide, anti-aging; can prevent red blood cell hemolysis and promote the reduction of methemoglobin and so on.

(2) It can cause a protective effect on leukopenia caused by radiation, radiopharmaceuticals or antineoplastic drugs; it can combine with toxic compounds, heavy metal ions or carcinogens entering the body to promote their excretion from the body and play a role in neutralization and detoxification ; It is clinically used to relieve the poisoning of oxides, carbon monoxide, heavy metals or organic solvents; it can inhibit the occurrence of alcoholic fatty liver caused by excessive drinking.

(3) It can prevent skin aging and pigmentation, reduce the formation of melanin, and improve the skin's antioxidant capacity.

(4) It can regulate the imbalance of acetylcholine and cholinesterase and play an anti-allergic effect. It can alleviate the symptoms caused by hypoxemia, nausea and liver disease, and can improve and treat corneal diseases.

Tag: Glutathione GSH, Raw Materials

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